Endocrine Abstracts

Background: Obstructive sleep apnoea (OSA) and polycystic ovary syndrome (PCOS) are associated with significant comorbidities and commonly coexist. The primary aim of this study was to examine the relationship between OSA and quality of life (QoL) in women with PCOS.Study design: Observational cross-sectional study.Methods: Women with PCOS were recruited from a single secondary care centre in the UK. PCOS was diagnosed according to...

Background: 25 hydroxy vitamin D (25(OH)D) vitamin levels are positively associated with bone mineral density and season, time of day and sun exposure duration influence its synthesis. Variations in daylight throughout the year and zenith angle, depending on the latitude of residence, influence u.v. solar radiation which is closely related to serum 25(OH)D levels. The aim of this study was to investigate the degree of seasonal variation of 25(OH)D serum levels in a population-...

Introduction: To evaluate the impact of a long-term telemonitoring programme for patients with type 2 diabetes mellitus (DMT2) on glycaemic control and lipid disorders.Methods/design: In the Greek pilot of a prospective, randomised, single-blinded, multicentre study 154 patients with DMT2, HbA1c >53 mmol/mol (7.0% according to NGSP) and capable of using the telemonitoring device, were studied after randomly assigned in the telemonitoring (IG) (n<...

Introduction: Type 1 DM (T1DM) has been associated with low bone mineral density (BMD) measured by dual energy X-ray absorptiometry (DEXA) but not with quantitative computed tomography (QCT). QCT provides a three-dimensional image and measures bone’s volume directly as density, independent of the surrounding tissues. The purpose of this study was to evaluate BMD in patients with T1DM using DEXA and QCT.Methods/design: We studied 81 patients with T1D...

Introduction: Limited data exists regarding testosterone levels in type 1 diabetes mellitus (T1DM). The objective of this study was to evaluate serum sex steroids levels and body composition using dual energy X-ray absorptiometry method (DEXA) in male patients with T1DM.Methods/design: We studied 36 male patients with T1DM (group D) (age: 35.3+11.66, years) and 35 healthy control (group C) matched for age, sex, and BMI. In both groups waist circumference...

Introduction: Empty sella syndrome (EES) is a condition often discovered incidentally, where the sella turcica, the structure containing the pituitary gland, appears to be empty. Patients either remain asymptomatic or, rarely, manifest signs of declined pituitary function. Patients experiencing hypopituitarism are offered hormonal replacement. Autopsy studies estimated a 5% EES prevalence among healthy individuals.Case report: A 68-year-old post-menopaus...

Introduction: Cushing’s syndrome is a rare (0.004%) hormonal disorder, which develops due to hypercortisolaemia. Cushing’s disease refers to a corticothroph cell pituitary tumour overproducing ACTH, which induces abnormally increased cortisol production from the adrenal glands. Cushing’s disease is a causative factor of osteoporosis, hypertension, glucose intolerance and dyslipidaemia.Case report: A 50-year old woman was referred to our de...

Background and objectives: Medullary thyroid carcinoma (MTC) originates from thyroid C-cells and is a calcitonin (CT) secreting tumour with aggressive behaviour. Surgery is recommended in all patients with basal or calcium-stimulated CT values of 100 pg/ml or higher due to the high probability of MTC. The objective of this study was to investigate the utility of calcium stimulation test for CT in order to distinguish MTC from C-cell Hyperplasia (CCH) preoperatively and to exam...

Introduction: Diagnostic and post-therapy radioiodine whole body scan (WBS) is used in the follow-up of differentiated thyroid carcinoma (DTC) for the detection of local recurrence or remote metastasis. We report a case of false-positive uptake of radioiodine WBS.Case report: A 37-year-old female patient underwent subtotal thyroidectomy for multinodular goitre and histology revealed multifocal papillary thyroid carcinoma, of follicular type with three fo...

Objective: Menopausal transition has been associated with an increased risk of cardiovascular disease (CVD), mainly attributed to atherogenic dyslipidaemia, central obesity and insulin resistance. Whether arterial hypertension (AH) also contributes to menopause-associated CVD is currently unknown. The aim of this study was to systematically investigate and meta-analyze the best available evidence regarding the association between early menopause (EM) and AH risk.<p class="...